Luteal Phase Dysfunction

Department of Clinical Science, Division of Ob. During the time of implantation, pinopodes appear on the endometrial surface. The precise function of these structural markers of endometrial receptivity is not known, but it is generally believed that they play a role in the implantation process.

who did endometrial dating according to the Noyes criteria,(2) considering as out-of-phase a delay of 3 days or Filho JH, Cedenho AP, Freitas V. Correlation between endometrial dating of luteal phase days 6 and 10 of the same menstrual cycle. Rev Paul Med ;(3)

Received Sep 2; Accepted Nov 6. Materials and methods Prospective, self-controlled study. The thirty-five volunteers were studied for two cycles: Endometrial biopsy was performed on day 6 after ovulation for histological dating and morphometric study. Results No statistical differences between histological dating and the endometrial thickness in the control and GnRH antagonist-treated cycles. All morphometric parameters were also not different. Conclusion GnRH antagonist has no effect on the endometrium of regularly menstruating women as assessed by either histological dating or morphometric analysis.

The role of GnRH agonist is to prevent premature LH surge which is associated with cycle cancellation.